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Why is there frank blood in my IUPC?

Frank blood returning in the amniolumen of an IUPC is most likely evidence of extraovular placement. The catheter is shearing between the membranes and the decidua, possibly perforating the placenta.

Once adequate cervical dilation has been reached and the amniotic membranes have been ruptured, IUPCs are placed into the amniotic sac with the fetus.

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The practitioner attempts to direct the catheter inside the amniotic sac but this is not always achieved. In fact, 14-38% of the time, regardless of practitioner experience, IUPCs are placed outside the membranes-extraovular, between the chorionic membrane and the decidua (endometrial lining)
i,ii. If an amniotomy has been done, care must be taken to insert the catheter through the opening created or it will be extraovular.

If frank red blood is seen in the lumen the practitioner should withdraw the device and reposition it, without violating more of the placenta, starting a dangerous amnioinfusion, or relying on inaccurate readings.


Frank Blood in Amniolumen

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Why haven’t I seen blood in catheters before?

Extraovular placement has just recently been discovered and documented.  It was not reported previously and blood has not been seen flashing back in catheters because one can’t see through opaque transducer-tipped IUPCs and fluid-filled systems are inserted primed with fluid.  To see flashback in an IUPC one must take steps to see it or use an IUPC designed to allow flashback.

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Is there a danger with extraovular placement?


Is there a danger with extraovular placement?


Yes, a danger does exist if the catheter is placed outside of the membranes. The most common complication of extraovular placement is placental perforation, which can lead to excessive bleeding, DIC, fetal heart rate abnormalities and artifactual waveforms
iii. In addition, if amnioinfusion is required, fluid is forced between the membrane and the decidua, greatly increasing the risk of placental abruption.

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Can I prevent extraovular placement?

The rate of extraovular placement can be minimized if several steps are taken. The practitioner should pay careful attention to make an adequate amniotomy and direct the catheter into that opening. Also, when advancing the catheter, minimal resistance should be encountered (unless the fetal head is wedged in the maternal pelvis at the outlet). Thus, if resistance is encountered, the catheter should be withdrawn and redirected.

The best way to confirm proper placement is to watch for a flashback of amniotic fluid in the IUPC amniolumen. If a flashback of frank-red blood is seen, the operator should withdraw and redirect the catheter. A study has shown that 86% of the time, after a blood flashback is seen and the catheter is withdrawn and repositioned up to three (3) times, the catheter will be positioned correctly within the amniotic sac.

To do this use an IUPC with a clear amniolumen or remove the amnioport cap from catheters with opaque amniolumens so fluid can be seen flowing from the amnioport. If you are using a fluid-filled system, insert the catheter without pre-priming it and allow the flashback of amniotic fluid to fill the lumen. If the catheter is not specifically designed for amniotic fluid flashback, make sure you leave the cap off the amnioport or fluid cannot flashback.

Does any blood flashback indicate improper placement?

It is important to decipher between frank blood (bright red blood) and blood-tinged fluid. The majority of the time frank blood flashback will be consistent with extraovular placement. However, other possibilities could be the cause of blood-tinged fluid in the catheter, such as blood present in the vagina or at the cervix secondary to labor changes of the cervix. This small amount of blood can be introduced into the catheter upon insertion and when mixed with amniotic fluid, appear to be a significant "blood flashback". Thus, when considering repositioning the catheter, it is important to consider the ease of insertion.

Upon catheter removal, the catheter tip can also be examined for evidence of blood or placental tissue-consistent with extraovular placement, or vernix-consistent with intraamniotic placement.

Are all catheters susceptible to extraovular placement?

It is important to remember that ALL intrauterine pressure catheters have a tendency for extraovular placement and that it happens regardless of operator experience unless steps are taken to prevent it.

If there is blood in the catheter can I reposition it?

Yes, the amniolumen where the blood flashback is seen is separate from the closed-system measuring the pressure within the uterine cavity. The only concern is that if a significant amount of blood is introduced into the lumen and is not flushed appropriately, the blood may clot and make amnioinfusions difficult or impossible. But, if the catheter is repositioned within the amniotic sac and communicating freely with amniotic fluid, the pressure readings will be accurate, regardless of the presence of blood.

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What catheters are designed for fluid flashback?

The Koala’s clear amniolumen and hydrophobic amnioport cap allow practitioners to verify proper placement, by observing flashback of amniotic fluid.  The catheter is marked to remind the practitioner to pause for flashback while inserting when only 10-12 cm of the catheter has been introduced within the uterine cavity, limiting the placental violation before it is withdrawn and redirected if it has been placed extraovular.

What the Koala IUPC offers, unlike any other catheter on the market, is the ability to confirm placement.  This feature may prevent dangerous amnioinfusions, placental abruptions and perforations, fetal heart rate abnormalities and artifactual waveforms when making important clinical decisions.


What the Koala IUPC offers, unlike any other catheter on the market, is the ability to confirm placement.  This feature may prevent dangerous amnioinfusions, placental abruptions and perforations, fetal heart rate abnormalities and artifactual waveforms when making important clinical decisions.

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What resources or training programs are available on IUPC placement?

Clinical Innovations offers IUPC placement training from our Medical Director, Ross McQuivey M.D. and our Clinical Nurse Specialist, Dianne Wagner.  We also have articles, quick reference material, and a study bibliography available on our website.  Please click here.

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REFERENCES

i Wallace, WD., Lind, B., "Extraovular Placement of Intrauterine Pressure Catheters in Laboring Patients", 4th World Congress of Perinatal Medicine; Buenos Aires, Argentina; April, 1999.
ii Sciscione, A., et al., "A Randomized Prospective Trial of Two Types of Intrauterine Pressure Catheters and the Rate of Extra-Ovular Placement", American J. of Obstetrics & Gynecology, January 2000. 
iii Lind Brent K., "Complications caused by extramembranous placement of intrauterine pressure catheters", American J. of Obstetrics & Gynecology, April 1999.50

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